Publications

Professor Wei Wang has published over 360 papers in leading journals including Nature Catalysis, Nature Communications, Nature Cell Biology, JACS, Angewandte Chemie International Edition, and others.

The group’s work covers organic synthesis, chemical biology, and drug discovery, contributing significantly to the development of novel chemical tools and targeted therapeutics.

Full list in Google Scholar.

ACS Chem. Biol. (2025)

Dual-Performing Vinyltetrazine for Rapid, Selective Bioconjugation and Functionalization of Cysteine Proteins

Chang, M.; Xu, H.; Dong, Y.; Gnawali, G.; Bi, F.; Wang, W.^*

ACS Chem. Biol. 2025, 20, 153-161.

Angew. Chem. Int. Ed. (2024)

Senolysis Enabled by Senescent Cell-Sensitive Bioorthogonal Tetrazine Ligation

Chang, M.; Dong, Y.; Xu, H.; Cruickshank-Taylor, A. B.; Kozora, J. S.; Behpour, B.; Wang, W.^*

Angew. Chem. Int. Ed. 2024, 63, e20231542.

J. Med. Chem. (2024)

Selective Elimination of Senescent Cancer Cells by Galacto-Modified PROTACs

Chang, M.; Gao, F.; Gnawali, G.; Xu, H.; Dong, Y.; Meng, X.; Li, W.; Wang, Z.; Lopez, B.; Carew, J. S.; Nawrocki, S. T.; Lu. J.; Zhang, Q.-Y.; Wang, W.^*

J. Med. Chem. 2024, 67, 7301-7311.

Chem (2023)

Direct Insertion into the C–C Bond of Unactivated Ketones with NaH-mediated Aryne Chemistry

Lou, F.; Li, C.; Peng, J.; Zhou, Y.; Gui, J.; Chen, L.; Yin, Y.; Zhang, X.; Hu, Y.; Chen, X.; Liu, X.; Chen, X.; Z.-X, Yu; Wang, W.^*; S.-L. Zhang

Chem 2023, 9, 2620-2636.

J. Am. Chem. Soc. (2023)

Infrared Light-induced Anomalous Defect-mediated Plasmonic Hot Electron Transfer for Enhanced Photocatalytic Hydrogen Evolution

Lian, Z.; Wu, F.; Zi, J.; Li, G.; Wang, W.^*; Li, H.

J. Am. Chem. Soc. 2023, 145, 15482–15487.

J. Am. Chem. Soc. (2023)

Bioorthogonal PROTAC Prodrugs Enabled by On-Target Activation

Chang, M.; Chen, J.; Pontigon, D.; Gnawali, G.; Xu, H.; Wang, W.^*

J. Am. Chem. Soc. 2023, 145, 14155–14163.

Highlighted in Nature Chemical Biology “Research Highlights”

Acta Pharm. Sin. B (2023)

Building Bioorthogonal Click-release Capable Artificial Receptors on Cancer Cell Surface for Imaging, Drug Targeting and Delivery

Chen, J.; Ji, P.; Gnawali, G.; Chang, M.; Gao, F.; Xu, H.; Wang, W.^*

Acta Pharm. Sin. B 2023, 13, 2736-2746.

Nat. Commun. (2022)

Selective Skeletal Editing of Polycyclic Arenes Using Organophotoredox Dearomative Functionalization

Ji, P.; Davies, C. C.; Gao, F.; Chen, J.; Meng, X.; Houk, K. N.; Chen, S.; Wang, W.^*

Nat. Commun. 2022, 13, Article number: 4565.

Angew. Chem. Int. Ed. (2020)

Potent Dual BET/HDAC Inhibitors for Efficient Treatment of Pancreatic Cancer

He, S.; Dong, G.; Li, Y.; Wu, S.; Wang, W.^*; Sheng, C.

Angew. Chem. Int. Ed. 2020, 59, 3028-3032.

Selected as ‘hot’ paper and journal cover

Nat. Catal. (2019)

Practical Synthesis of C-1 Deuterated Aldehydes Enabled by NHC Catalysis

Geng, H.; Chen, X.; Gui, J.; Zhang, Y.; Shen, Z.; Qian, P.; Chen, J.; Zhang, S.; Wang, W.^*

Nat. Catal. 2019, 2, 1071-1077.